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HPLC of Peptides and Proteins

Engels | Druk: 2004 ed. | Hardcover | 9780896039773 | 414 pagina's

Marie-Isabel Aguilar, SSS Marie-Isabel Aguilar - 9780896039773


Engels | Druk: 2004 ed. | Hardcover | 9780896039773 | 414 pagina's

The introduction of high-performance liquid chromatography (HPLC) to the analysis of peptides and proteins some 25 years ago revolutionized the biological sciences by enabling the rapid and sensitive analysis of peptide and protein structure through the exquisite speed, sensitivity, and resolution that can be easily obtained. Today, HPLC in its various modes has become the pivotal technique in the characterization of peptides and proteins and currently plays a critical role in both our understanding of biological processes and in the development of peptide- and protein-based pharmaceuticals. The number of applications of HPLC in peptide and protein purification continues to expand at an extremely rapid rate. Solid-phase peptide synthesis and recombinant DNA techniques have allowed the production of large quantities of peptides and proteins that need to be highly purified. HPLC techniques are also used extensively in the isolation and characterization of novel proteins that will become increasingly important in the postgenomic age. The design of multidimensional purification schemes to achieve high levels of product purity further demonstrates the power of HPLC techniques not only in the characterization of cellular events, but also in the production of pepti- and protein-based therapeutics. HPLC continues to be at the heart of the analytical techniques with which scientists in both academia and in industry must arm themselves to be able to fully characterize the identity, purity, and potency of peptides and proteins.


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HPLC of Peptides and Proteins Engels | Druk: 2004 ed. | Hardcover | 9780896039773 | 414 pagina's
Druk2004 ed.
Verschijningsdatumdecember 2003
Aantal pagina's414 pagina's
AuteurMarie-Isabel Aguilar | SSS Marie-Isabel Aguilar
Co-auteurSSS Marie-Isabel Aguilar
RedacteurMarie-Isabel Aguilar
UitgeverHumana Press Inc.
Extra groot lettertypeNee
Gewicht1720 g
Verpakking breedte155 mm
Verpakking hoogte32 mm
Verpakking lengte228 mm

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